Alpha 1 Antitrypsin Deficiency & COPD
Alpha-1
antitrypsin deficiency is a genetic disorder
that is passed on in families and affects the lungs, liver and skin. When this
condition affects the lungs, it causes COPD. There is no cure, but treatment
can help people with Alpha-1 antitrypsin deficiency manage their symptoms and
live a better life. The preliminary symptoms are shortness of breath following
mild activity, reduced ability to exercise, and wheezing. Other signs and
symptoms include unintentional weight loss, recurring respiratory infections,
fatigue, and rapid heartbeat upon standing. Affected individuals often develop emphysema,
which is a lung disease caused by damage to the small air sacs in the lungs.
Alpha-1 antitrypsin deficiency accounts for 1 to 2% of all cases of chronic
obstructive pulmonary disease.